#胰臟癌👫 #標靶治療🎯 開發 #抗癌藥物 15年磨一劍 想想那台 #小挖土機🚢 ⛏
胰臟癌是相當棘手的癌症,確診時,患者的腫瘤細胞通常已經轉移,增加治療難度...
當年 #臺大醫院 醫師與本院 #李文華 院士分享臨床治療心得時,李院士意識到:若能結合臨床經驗與科學研究,有助於解決這個攸關全人類健康的重大問題,挽救更多生命!
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在李文華院士帶領下,由本院 #基因體研究中心、中國醫藥大學新藥開發中心組成的跨機構研究團隊,歷經多年研究,於今(2021)年宣布👉破解胰臟癌細胞的訊息傳遞機制,並且合成出 #多胜肽分子,可以 #阻斷致癌訊號傳遞,#抑制癌細胞的生長與轉移。
🎯實驗顯示能有效延長胰臟癌小鼠的壽命,而且不會影響正常的免疫反應。研究成果已發表在國際期刊《科學轉譯醫學》(Science Translational Medicine)
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💥原來,在胰臟癌細胞表面大量出現的受體(存在於細胞膜上的蛋白質分子)「IL-17RB」,容易兩兩結合,形成同質雙聚體,遇到配體IL-17B後,就會召喚激酶「MLK4」,催化蛋白質磷酸化,有如按下開關般,啟動後續一連串致癌訊號🔔 🔔 🔔
為了阻斷癌化訊號傳遞🔕🔕🔕,研究團隊設計出多胜肽分子,它是一組胺基酸序列,可在細胞內特定位置取代激酶MLK4,阻止激酶與受體交互作用。相較於團隊2015年研發出的抗體藥物,治療更為精準,而且不影響患者免疫力。
目前團隊致力研發效果更穩定的 #小分子藥物,以利胰臟癌患者進行 #標靶治療。
🔴新聞稿:https://reurl.cc/v5oAoo
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Pancreatic cancer is known to be vicious, pancreatic ductal adenocarcinoma (PDAC) is the type that accounts for 95% of pancreatic cancer and so far it is still incurable. An added fact makes PDAC doomed lies in its tendency to have metastasis, meaning cancer cells have already spread to other organs, when diagnosed.
In this study, “The results not only establish a clear pathway of how proximal signaling of IL-17RB occurs, but also provides insight into how this pathway is clinically significant in many pancreatic cancers.”, commented Dr. Chun-Mei Hu.
🔴Press Release:https://reurl.cc/dV9A8g
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研究團隊成員:中央研究院李文華院士、胡春美助研究員和沈家寧副研究員;中國醫藥大學吳恒祥助理教授;臺大醫院田郁文醫師、張毓廷醫師、章明珠醫師和鄭永銘醫師。👏👏👏
Team members are from Academia Sinica (Dr. Wen-Hwa Lee, Dr. Chun-Mei Hu and Dr. Chia-Ning Shen), China Medical University (Dr. Heng-Hsiung Wu) and National Taiwan University physicians (Dr. Yu-Wen Tien, Dr. Yu-Ting Chang, Dr. Ming-Chu Chang and Dr. Yung-Ming Jeng.👏👏👏
#研究團隊十五年青春 #迎戰癌中之王 #存活率最低的癌症
同時也有9部Youtube影片,追蹤數超過6萬的網紅BlueBerries詭計星的頻道,也在其Youtube影片中提到,秀逗各方面都比法師強許多, 高破防+穿刺, 強勁專武, 無須元素球不卡技能, 多了免死+5個獨特技能. 唯一弱點是沒有魂爆, pvp遇到坦職就只能拼重力斬秒or自殺. 秀逗需要基礎魔攻, 也就是存入/附魔Int或魔攻越高, 就能白嫖高破防+穿刺. 每月存入%不計入, 是不是親平民呢~ Slaye...
dr meaning 在 Facebook 的精選貼文
Video - Tasha’s Pei-Pei
I don’t know a single Mandarin . So does Dr Halina but yet we send our girls to SJKC .
Why ? - Because we understand the importance of Mandarin .
It will be an advantage for the girls in years to come .
Furthermore it’s good to master many languages including Arabic and French.
But for those who plan to send your kids to a SJKC School ...it takes lots of effort and commitment .
Firstly you are unable to teach them .
You don’t really know what they are learning as all subjects are in Mandarin.
They certainly need extra classes.
Bella & Tasha have extra classes 4x a week .
They usually able to truly speak & write fluently when they are in Standard 3 .
Anything earlier - don’t expect too much .
It takes time for them to adapt as Mandarin is a tough language .
Bella is quite proficient in Mandarin but Tasha is getting there .
Different pronunciation will bring about different meaning .
It’s challenging but will be totally worth it.
Sending to SJKC from an early age is the only way for them to be fluent .
That’s the best way - surrounded by Chinese friends and environment .
Also I loved SJKC teachers - they are as strict as can be .
Memang garang - Haha
Just sharing
Salam Everyone
Love As Always
PS - Adam & Noah will soon go to a Chinese
Kindergarten too . So will Eusoff & Emelia .
That’s the plan .
Read all the plans for my kids in ‘ My Way Of Parenting’ Book .
Only at Shopee - drsheikh.os (Link at Bio)
dr meaning 在 thefamily.uk Facebook 的最佳貼文
I PRAY FOR YOU... Surah Al-Mursalat is one of my favourite surahs in the Quran, especially the version recited by @omarhishamalarabi. I must confess that when I first read this surah many many years back, I didn’t take the initiative to read the meaning of this surah. When I came to carefully learn its meaning, it gave me goosebumps!
I’m sure I’m not the only one who feels frightened when hearing about The Last Day or The Last Hour. The day when there will be violent storms, great shaking of earthquakes. Thinking about the last hour, I reflected upon my life. They say that life is the result of our own actions. I couldn’t agree more! The seeds of our actions we plant in this world...we will taste its fruits in the life after. Whether the fruit is sweet or sour, we’re solely accountable for it!
And glad tidings from Allah be to those who bear patience. Patience when facing tough times. Patience when dealing with the loss of loved ones. Patience when suffering with great illness. Allah has guaranteed those who are patient that He will give them rewards without measure. Patience and victory are twin brothers. Allah promised those who are patient that He is with them and will grant them a clear victory!
I’m addressing you...anyone who is affected by sickness or illness, especially my dearest sister Mrs Mom @thefamily.uk. I sincerely pray for you: “May The Almighty, who is capable of making the impossible possible, heal you and give you strength. May He grant you a cure. May He grant you miraculous recovery. May the love, peace and comfort be with you as you battle this illness. May He cure you and reward you for all the suffering that you’re going through. May He grant you a complete return to normal health and make you even better than you were before.” 💝
#sayAameen #PrayForMrsMom #drauntieuk
p/s: Written by Mrs Mom’s elder sister Dr Auntie
dr meaning 在 BlueBerries詭計星的頻道 Youtube 的最佳貼文
秀逗各方面都比法師強許多, 高破防+穿刺, 強勁專武, 無須元素球不卡技能, 多了免死+5個獨特技能. 唯一弱點是沒有魂爆, pvp遇到坦職就只能拼重力斬秒or自殺.
秀逗需要基礎魔攻, 也就是存入/附魔Int或魔攻越高, 就能白嫖高破防+穿刺.
每月存入%不計入, 是不是親平民呢~
Slayers are way better than AM, she had more Ignore MDEF/MPEN parameter, Stronger glove weapons, No need orbs to cast skill meaning she can cast faster, also with Unique Anti-Fatal buff & 5 Compound Magic Spell.
The only weakness seems so far, it had no Soul Expansion to counter Tank Class, need to gamble on Heavy Slave for 1-Hit Kill or Suicide lol.
Slayers need EQ/Enchant/Deposit MATK & Int to boost Base Matk for Bonus Ignore MDEF & MPEN.
No MATK% deposit invloded, Nice F2P Classes.
Part of the video used: Dr. Purky
https://www.facebook.com/drpurky/
& CN/SEA discuss group, some of them people sent me not sure did I miss credit someone else.
dr meaning 在 Wisdom Bread 智慧麵包 Youtube 的最佳貼文
一不小心,你也許就患上了「彼得潘症候群」...
講者是著名的心理學教授喬登·彼得森。
►Special thanks to Dr. Jordan B Peterson for this wonderful interview.
https://www.youtube.com/user/JordanPetersonVideos
標題:為什麼大多數男人總是渾渾噩噩,無所作為?► 這會是你人生一大啟發 - Dr. Jordan B Peterson 喬登·彼得森(中英字幕)
https://youtu.be/QGFnNgdRu_4
喬登·彼得森是著名的心理學教授,在YouTube擁有280萬粉絲。
有興趣可以看看教授的暢銷著作 12 Rules for Life 《生存的12條法則》,一年內售出超過300萬本。
Speaker: Dr. Jordan B Peterson 喬登·彼得森
#智慧麵包 #喬登彼得森 #彼得潘症候群
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► 此頻道沒有開啟Youtube廣告。
所有影片為教育用途,希望讓更多人能夠受到啟發,學習和受益。
如果您認同我們的理念,請轉發此影片。
- Wisdom Bread 智慧麵包
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Speaker: Dr. Jordan B Peterson 喬登·彼得森
Special thanks to Dr. Jordan B Peterson for this inspiring speech
► 原完整版影片:(2小時半)
2017 Maps of Meaning 11: The Flood and the Tower
https://www.youtube.com/watch?v=T4fjSrVCDvA
剪輯/翻譯/字幕:Wisdom Bread 智慧麵包
Music & Footage used in this video licensed to Wisdom Bread
► 訂閱Wisdom Bread智慧麵包??
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► 更多啟發、智慧、勵志影片 ??
為什麼要尋找人生目的? ► 這是一則意義深遠的故事...Dr. Robert Quinn(中英字幕)
https://youtu.be/gPgBGlz-9-0
別讓你的第16秒留有遺憾 ► 這位榮譽生的演講,或許會讓你反思... - Kyle Martin(中英字幕)
https://youtu.be/H6Vz3vCgoJA
「總會有人潑你冷水,總會有人等著看你失敗...」當你感到迷失的時候,成為左邊那隻鯊魚吧 ► - Meredith Vieira 梅雷迪思.維埃拉(中英字幕)
https://youtu.be/y5Yx2he82X4
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dr meaning 在 SARAH & JASON Youtube 的最佳解答
We've been wanting to Vlog the experience of going to the supermarket
But to the shop and to stay clean and to film all at the same time just seems like a load of effort and a load of worry
Having seen Dr. Jeffrey VanWingen's vlog about cleaning groceries inspired us to show you how we do it (how Jason does it)
https://www.youtube.com/channel/UCldCyQOF-hwkVXEsF5-oRFg
It's actually much more easy-going now, since the situation in Hong Kong seems to be somewhat under control
Nevertheless it's always good to be prepared, and it never hurt to do a little more (if you can)
You should take what we say with a pinch of salt
Jason does like to clean, more accurately, Jason used to like doing a bit of cleaning
Jason: I think I've done enough cleaning for a good many years, I'm looking forward to not cleaning anything soon
Sarah: not true, he's pretty OCD, pretty meaning "extremely, top 5%, cannot be saved "OCD, so you tell me if he'll ever stop cleaning???
Have a lovely lovely weekend
Happy Mother's Day
Maybe you can all do the dishes for your mothers or your wives or the future mother of your kids… You know what we mean???
#CleanGroceries #FruitAndVeg
#COVID19free #Can #Plastic
#Clothes #Shoes #CleanCar #OCD
#買餸 #餸菜清洗 #完美示範 #消毒 #新冠肺炎
#水果 #蔬菜 #肉 #魚 #罐頭 #紙包裝
#衫褲鞋襪 #洗車 #乾淨
#StayCalm #StayPositive
#StaySafe #StayHealthy
#LookAfterYourself #LookAfterEachOther
#KeepUpTheHardWork