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在journal bmc這個產品中，有37篇Facebook貼文，粉絲數超過13萬的網紅窩窩 wuowuo，也在其Facebook貼文中提到， 那粒不是眼睛⋯⋯是我肛門啦 0.0 #日曆小學堂 #每天帶你認識台灣原生種 海裡遇到全身尖尖刺的刺冠海膽，又稱作魔鬼海膽，中間還有一粒魔鬼之眼正瞪著你⋯⋯喔不！那一粒根本看不到你，只有可能無差別開射～屎！！ 魔鬼海膽的肛門長在那粒上面，位於金黃色圈的中央。這顯眼的構造稱作「肛乳突」，你以為是故意...
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窩窩 wuowuo By 窩窩 wuowuo

2021-09-26 10:49:05 有 424 人按讚
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那粒不是眼睛⋯⋯是我肛門啦 0.0
#日曆小學堂 #每天帶你認識台灣原生種

海裡遇到全身尖尖刺的刺冠海膽，又稱作魔鬼海膽，中間還有一粒魔鬼之眼正瞪著你⋯⋯喔不！那一粒根本看不到你，只有可能無差別開射～屎！！

魔鬼海膽的肛門長在那粒上面，位於金黃色圈的中央。這顯眼的構造稱作「肛乳突」，你以為是故意要秀給你看（？）但其實是牠全身防護用的刺棘又多又長，得要靠這突出的構造，讓屎飛高高、去遠方，才不會卡在刺上，不弄髒自己的身體。

這位愛乾淨的海膽也幫珊瑚清藻類，「喀滋、喀滋」一口一口吃掉與珊瑚爭地的藻類！但如果牠的數量過剩，也可能導致其他生物無藻可食、破壞礁石，有害於珊瑚礁生態。

魔鬼還是天使？有時就在轉瞬之間。

#刺冠海膽 #臺灣原生種
Diadema setosum

............................................
ref. 台灣生命大百科 / Diadema setosum Leske, 1778、BMC / Journal of Biological Research-Thessaloniki、環境資訊中心 / 臺灣常見的海膽簡介－魔鬼的眼睛
............................................

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2022｜島嶼共居 x 動物日曆
https://wuo.pros.is/3nl2h2
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#365頁島嶼動物全彩插畫
#買日曆支持窩窩動保教育

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新思惟國際 By 新思惟國際

2021-08-20 10:00:46 有 41 人按讚
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【🔔 #醫學論文與寫作工作坊 上課囉！】
五種研究必學統計一天搞懂，SCI 發表在望！
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Dr 文科生 By Dr 文科生

2021-05-27 20:00:46 有 553 人按讚
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哮喘並非想像中的輕鬆

在日常問診的時候，不難發現很多病人都有不同程度的長期咳嗽問題。

有些病人小時候有哮喘，每當換季或做運動時需要用到一些藥物減輕呼吸困難，但長大後便漸漸穩定下來。但有些病人卻未必那麼幸運，哮喘病情一直以來都未曾好過，仍然常常受哮喘困擾。

那麼，到底什麼是哮喘？跟一般感冒的咳嗽有什麼分別？

哮喘是是過敏鐵三角（Atopy）的其中一員
1. 哮喘（Asthma）
2. 鼻敏感（Allergic Rhinitis）
3. 濕疹（異位性皮膚炎）（Atopic Dermatitis）

哮喘大部分都是因過敏反應而產生免疫細胞和因子，例如Eosinophil, interleukin-4 and 5和IgE等，令呼吸道肌肉收縮和氣管收窄，導致呼吸困難的徵狀。過敏原因很多，可以是天氣轉變、常見的花粉、塵蟎和化妝品等等。

長期不受控的哮喘可引致呼吸道慢性炎症，長遠可引致呼吸道組織變異而令哮喘狀況惡況而不受控制，令藥物的效果變差。所以於哮喘早期時盡快治療和良好的長期控制便極為重要。

在香港，不少人都對哮喘認識不深，很多都把早期或慢性哮喘的徵狀當作是一般天氣轉變或小感冒去處理。但這樣是無法長遠控制好病情的。

跟大眾固有印象不同的是，常見哮喘徵狀並不只是咳嗽；胸口痛、喘嗚（Wheezing）、呼吸困難或過速、半夜咳醒或睡眠質素偏差、運動時體能不佳而動輒要停下來休息喘氣等都是常見的徵狀。

那麼，怎麼知道自己是不是患有哮喘？這種情況下便要諮詢醫生的意見，如有需要便會安排進行肺功能測試，如結果是呼吸道受阻而在使用藥物後有改善的話，便很可能有哮喘的問題。

一般來說，哮喘治療主要有以下幾種
1. Short Acting Beta-2 Receptor Agonist（SABA）
2. Short Acting Muscarinic Antagonist （SAMA）
3. Long Acting Beta-2 Agonist （LABA）
4. Long Acting Muscarinic Antagonist （LAMA）
5. Inhaled Corticosteroids （ICS）
6. Leukotriene Antagonist

這些藥物對哮喘到底有什麼功效？而什麼人應為用什麼藥物控制？

首先你需要先諮詢醫生再進行肺功能測試，判斷是否有氣道受阻（Airway obstruction）或氣管抽搐（Bronchospasm）的問題，而這些問題亦可透過氣管擴張劑（bronchodilator）減輕從而改善肺功能。

幾十年前哮喘來來去去都是靠俗稱為藍色噴霧的短效氣管擴張劑（SABA）例如salbutamol。一般來說輕度哮喘的確可以靠SABA在有徵狀時，例如換季、做運動或過敏時減輕徵狀令生活不致太受影響。然而研究發現高達七成的哮喘病人並未能良好的控制哮喘徵狀。[1][2]

很多人都以為哮喘只需要發作時吸一吸氣管擴張劑便會好，但其實如果是中等至嚴重級別的哮喘，單靠短效氣管擴張劑並不能完全控制。SABA亦非沒有副作用，常見的副作用為心跳過速，當病人病情不穩需要不斷使用SABA時，便可能出現以下問題

1. 心跳過速至不適或頭痛
2. 生活質素被哮喘徵狀嚴重影響，例如半夜咳醒需要吸SABA或未能進行運動，因休息不足而經常疲累
3. 哮喘從根本上並未受到控制，長期炎症和過敏反應令氣道組織變異，導致哮喘持續惡化

因此近年愈來愈多新型藥物能提供長久的哮喘控制。當中以吸入性類固醇（ICS）和長效氣管擴張劑（LABA）最為革命性的發展。

吸入性類固醇針對身體因過敏反應所產生導致炎症和氣管收縮的問題，透過壓抑過敏和炎症而紓緩徵狀同時減少長期過敏發炎引致的氣道組織變異。

長效氣管擴張劑例如Salmeterol和Formoterol，跟短效最大的分別是，長效一天只要噴一至兩次，短效在中等至嚴重的患者可能需要每數小時噴上6次甚至更頻密，頻密地使用氣管擴張劑增加了副作用的產生和生活質素的影響。

傳統長效氣管擴張劑能產生長效藥力紓緩氣管收縮、咳嗽和呼吸困難的徵狀，務求達到改善生活質素，讓患者不用半夜醒來或日間經常要停下來吸SABA。近年更有新一代Ultra Long Acting beta2-agonist例如vilanterol，從而達至更穩定和長效的徵狀紓緩。

令人無奈的是，哮喘可以說是一場長期的戰爭，當你日以繼夜夜以繼日要噴氣管擴張劑時，不少患者都會感到無助令大家久而久之不再跟足醫生或藥劑師建議，間中不適才噴一下，令病情未能得到良好控制。

因此，另一個革命性的改變便是combined inhaler，近年不少吸入性哮喘藥物均為混合式，吸一次等於吸了兩種藥物，例如大家可能都見過的Fluticasone/Sameterol和Budesonide/Formoterol。較新的有超長效混合藥物，藥效可持續12-24小時，例如Fluticasone/Vilanterol。這些混合式藥物大大減少病人每天需要使用吸入器的次數，令更多病人更願意持續的使用，

最後想提提大家，使用吸入式噴劑的技巧非常重要，研究發現不少患者技巧欠佳令不少藥物只噴在口內無法成功到達氣管內[3]。近年不少新型吸入式device有特別設計改善這問題，由於種類太多，強烈建議你諮詢你的家庭醫生、護士或藥劑師建議以及讓醫護人員評估你的使用技巧。

視乎患者的臨床狀況，一些病人只需要間中用到SABA；一些病人需要用到SABA+SAMA；嚴重點的病人需要用到SABA+LABA+ICS；醫生可能建議病人使用不同的combination以控制哮喘，所以患有哮喘的話，請務必定期與家庭醫生跟進。

*新型藥物如生物製劑（IgE-inhibitor或Eosinophil Inhibitor或IL-4/5 Inhibitor）由於太複雜的關係便不在此講解，留待下次有機會再跟大家分享。

Reference
[1] Woodcock A, et al. (2017) Effectiveness of fluticasone furoate plus vilanterol on asthma control in clinical practice: an open-label, parallel group, randomised controlled trial. The Lancet

[2] Martyn R Partridge et al (2006). Attitudes and actions of asthma patients on regular maintenance therapy: the INSPIRE study. BMC Pulm Med.

[3] Lia Jahedi, et al (2017). Inhaler Technique in Asthma: How Does It Relate to Patients' Preferences and Attitudes Toward Their Inhalers? Journal of Aerosol Medicine and Pulmonary Drug Delivery.

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FindDocTV@FindDoc.com By [email protected]

2021-03-24 15:00:04 有 11,509 人看過 有 0 人喜歡
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生蛇 － 丁昭慧內分泌及糖尿科專科醫生＠FindDoc.com

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（一）什麼原因導致生蛇，和它有什麼病徵？ 00:06

（二）糖尿病與生蛇兩種病症會否互相影響？ 02:04

（三）生蛇有什麼後遺症？如何預防？ 03:09

(本短片作健康教育之用，並不可取代任何醫療診斷或治療。治療成效因人而異，如有疑問，請向專業醫療人士諮詢。)

參考資料：
1 Cohen, J. I. The New England Journal of Medicine, 369(3), 255-263 (2013).
2 Chua, J. V., & Chen, W. H. (2010). Herpes zoster vaccine for the elderly: boosting immunity. Aging health, 6(2), 169–176. https://doi.org/10.2217/ahe.10.5.
3 Johnson, R.W.. Expert Rev Vaccines, 9(3 Suppl):21-26 (2010).
4 CDC. Recommendations of the ACIP. MMWR Early Release 2008; 57. RR-5.
5 John, A. R. et al. Infect Dis Clin N Am, CNA, 31(4), 811–826 (2017).
6 Papagianni, M. et al. Diabetes Ther; 9(2), 545–550 (2018).
7 Muñoz-Quiles, C. et al. Human Vaccines & Immunotherapeutics; 13(11), 2606–2611 (2017).
8 Diabetes UK. Complications of diabetes, Available at: https://www.diabetes.org.uk/guide-to-diabetes/complications (Accessed on 1 July 2020)
9 Fasil, A. et al. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 12, 75–83 (2019).
10 Global report on diabetes. (2016). Geneva: World Health Organization.
11 Johnson, R. W. et al. BMC medicine, 8, 37 (2010).



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香港最全面醫療資訊影片平台，超過200位專科醫生、中醫、物理治療師、營養師等解答你的健康問題。搜尋全港各區醫生資料，即上FindDoc.com! At FindDoc, we aim to increase general public health awareness through our FindDocTV videos. Patients can make doctors’ appointments online using our platform Anytime Anywhere. FindDoc is Free and open to both patients and doctors.
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journal bmc 在 [email protected] Youtube 的最佳貼文

FindDocTV@FindDoc.com By [email protected]

2020-09-16 17:45:43 有 46,620 人看過 有 0 人喜歡
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周邊神經病變

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FindDoc WeChat : 快徳健康香港 FindDoc
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（一）周邊神經病變（peripheral neuropathy）的病因、症狀？

（二）如何分辨背痛和坐骨神經痛？

（三）甚麼是腕管綜合症？

（四）如忽視神經痛楚，會有甚麼嚴重後果？

（五）如何紓緩／治療神經痛楚？

（六）神經問題與缺乏維他命有關？


(本短片作健康教育之用，並不可取代任何醫療診斷或治療。治療成效因人而異，如有疑問，請向專業醫療人士諮詢。)

參考資料：
1. Hsieh, S.C. (1998). Brief Introduction to Peripheral Neuropathy. Medicine Today 25(11) 883-887
2. Martyn, C. N., & Hughes, R. A. (1997). Epidemiology of peripheral neuropathy. Journal of neurology, neurosurgery, and psychiatry, 62(4), 310–318. https://doi.org/10.1136/jnnp.62.4.310 Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074084/?page=1
3. Sindrup, S.H., Otto, M., Finnerup, N.B. and Jensen, T.S. (2005), Antidepressants in the Treatment of Neuropathic Pain. Basic & Clinical Pharmacology & Toxicology, 96: 399-409. doi:10.1111/j.1742-7843.2005.pto_96696601.x Retrieved from https://onlinelibrary.wiley.com/doi/full/10.1111/j.1742-7843.2005.pto_96696601.x
4. Ekabe, C. J., Kehbila, J., Abanda, M. H., Kadia, B. M., Sama, C. B., & Monekosso, G. L. (2017). Vitamin B12 deficiency neuropathy; a rare diagnosis in young adults: a case report. BMC research notes, 10(1), 72. https://doi.org/10.1186/s13104-017-2393-3 Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5273828/
5. Shibuya, K., Misawa, S., Nasu, S., Sekiguchi, Y., Beppu, M., Iwai, Y., Mitsuma, S., Isose, S., Arimura, K., Kaji, R., Kuwabara, S. (2014). Safety and efficacy of intravenous ultra-high dose methylcobalamin treatment for peripheral neuropathy: a phase I/II open label clinical trial. Internal Medicine, 53(17), 1927-1931. https://doi.org/10.2169/internalmedicine.53.1951 Retrieved from https://www.jstage.jst.go.jp/article/internalmedicine/53/17/53_53.1951/_article



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FindDocTV@FindDoc.com

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香港最全面醫療資訊影片平台，超過200位專科醫生、中醫、物理治療師、營養師等解答你的健康問題。搜尋全港各區醫生資料，即上FindDoc.com! At FindDoc, we aim to increase general public health awareness through our FindDocTV videos. Patients can make doctors’ appointments online using our platform Anytime Anywhere. FindDoc is Free and open to both patients and doctors.
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journal bmc 在 POPA Channel Youtube 的最佳貼文

POPA Channel By POPA Channel

2016-03-23 17:55:22 有 13,052 人看過 有 116 人喜歡
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之前我們曾嘗試從 BB 的角度出發，看看他們來到這個世界每日面對的新挑戰，但對新手父母而言，日以繼夜、夜以繼日地照顧小朋友，又何嘗不是天天面對不同難關？身心俱疲之餘，部份父母更會為了小朋友放棄自己的嗜好、減少出席朋友聚會等等，你以為會換來美好的親子關係，有助小朋友成長，但事實又是否這樣？

參考資料

Chau, V., & Giallo, R. (2014). The relationship between parental fatigue, parenting self-efficacy and behaviour: Implications for supporting parents in the early parenting period. Child: Care, Health and Development, 626-633.

Cooklin, A., Giallo, R., & Rose, N. (2011). Parental fatigue and parenting practices during early childhood: An Australian community survey. Child: Care, Health and Development Child Care Health Dev, 654-664.

Lesniowska, R., Gent, A., & Watson, S. (2015). Maternal fatigue, parenting self-efficacy, and overreactive discipline during the early childhood years: A test of a mediation model. Clinical Psychologist Clin Psychol.

Dunning, M., Seymour, M., Cooklin, A., & Giallo, R. (n.d.). Wide Awake Parenting: Study protocol for a randomised controlled trial of a parenting program for the management of post-partum fatigue. BMC Public Health, 26-26.

Weaver, C., Shaw, D., Dishion, T., & Wilson, M. (n.d.). Parenting self-efficacy and problem behavior in children at high risk for early conduct problems: The mediating role of maternal depression. Infant Behavior and Development, 594-605.

Rizzo, K. M., Schiffrin, H. H., & Liss, M. (2012). Insight into the Parenthood Paradox: Mental Health Outcomes of Intensive Mothering. Journal of Child and Family Studies J Child Fam Stud, 22(5), 614-620.

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POPA Channel

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幾個家長走埋一齊，將從閱讀所得的知識整合，化繁為簡，與大家分享正面育兒(POSITIVE PARENTING)的資訊。 ===================================== 幾年前，初為父母，第一次抱住自己的孩子，發覺養育、教育孩子，是一門高深學問。時代不同，父母對我們的一套，應用在自己孩子身上，亦未必適合。因而開始閱讀育兒書籍、兒童心理學等文獻，發現學術界近年對兒童成長發展的深入了解，其實對家長們極為實用。 但現今父母日日為口奔馳、回家要湊BB都已經筋疲力竭，哪有餘暇、精力去搜尋、閱讀又長又悶的學術文章？於是，我們幾個家長，以正面態度去養育孩子為前題，將自己從閱讀所得的知識，透過輕鬆易明的手法，與各位關心孩子成長發展的父母，分享實用資訊。 POPA Channel 亦因而誕生！ ===================================== Official Homepage: http://popa.hk Facebook Page: www.facebook.com/popachannel
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