June 29 is a day to recognise the bravery of those who live with #scleroderma.
4 years into scleroderma, weekly injection, frequent checkup and blood test..it doesn't get easier, but we learn how to live with it and praying hard that her condition doesn't worsen and affect her basic daily life.
While research is still going on to find a cure, we told her the pain you feel today will be your strength tomorrow, and your biggest strength will always be us - your family.
Spreading awareness is to let more people know more about the condition and seek treatment early, because it's rare and most cases only realised when they reach the later stage of the disease.
Once again, I'm thankful and will always remember friends who helped me and Yi He during our difficult times when she first diagnosed.
What is Scleroderma?
Scleroderma (sklair-oh-DUR-muh) is a rare autoimmune disease that involves the hardening and tightening of the skin and connective tissues.
同時也有2部Youtube影片,追蹤數超過3萬的網紅[email protected],也在其Youtube影片中提到,濕疹- 盧景勳皮膚科專科醫生@FindDoc.com FindDoc Facebook : https://www.facebook.com/FindDoc FindDoc WeChat : 快徳健康香港 FindDoc FindDoc Instagram:@finddochk (一)異位...
skin disease research 在 李木生醫師 Facebook 的最讚貼文
孫女從嬰兒時期就有異位性皮膚炎,心疼他因為癢而抓出許多血絲與常常皮膚紅腫。身為婦產科醫師的我,對這個疾病不甚了解,但最近開始閱讀這個疾病的相關知識,想與大家分享。
近二十年來,台灣的異位性皮膚炎的盛行率增加將近一倍, 有些研究顯示都市化和空氣污染會增加風險,也有些研究說媽媽在懷孕期間多吃魚會降低風險。
百分之八十的異位性皮膚炎始於5歲以下,而約有一半以上得異位性皮膚炎的小朋友,長大會”自己好” 但詳細原因不明,或許和早期疾病的控制有關。
異位性皮膚炎是一種皮膚的過敏反應,許多病人因爲皮膚天然保濕因子 (filaggrin) 不足的體質,造成過敏原更容易通過乾燥龜裂的皮膚,而誘發過敏反應,所以除了擦藥與(嚴重時)吃藥,保濕乳液對於預防復發非常重要,近幾年有些免疫阻斷劑的上市,讓對付嚴重異位性皮膚炎的 ”藥品軍火庫“ 又增加一些生力軍。
有家族病史的小朋友更容易得到異位性皮膚炎,代表基因也有關聯。約有60-70% 的異位性皮膚炎的病患,會有 Filaggrin 基因上的某些位點的突變 ,目前已知有數十個 Filaggrin 基因位點的突變,有趣的是,亞洲人與歐洲人突變的位點不盡相同。而台灣本土人口 Filaggrin 基因位點的突變,仍尚未被發表。
目前各國的皮膚科醫學會,都同意早期治療,藉以降低復發的強度與頻率,所以小朋友的皮膚如果常常乾紅癢,應該及早就醫診斷與治療。至於有家族病史但沒有發病的小朋友,是否該做Flaggrin基因檢測,而提早擦保濕乳液 ,是一個值得討論的題目。
#異位性皮膚炎
#保濕因子
#提早擦乳液
參考文獻
Chu C-Y et al. Taiwanese Dermatological Association consensus for the management of atopic dermatitis. Dermatologica Sinica. 2015 Dec 1;33(4):220–30.
Romieu I, Torrent M, Garcia-Esteban R, Ferrer C, Ribas-Fitó N, Antó JM, et al. Maternal fish intake during pregnancy and atopy and asthma in infancy. Clin Exp Allergy. 2007 Apr;37(4):518–25.
Irvine AD, McLean WHI, Leung DYM. Filaggrin mutations associated with skin and allergic diseases. N Engl J Med. 2011 Oct 6;365(14):1315–27.
Nutten S. Atopic Dermatitis: Global Epidemiology and Risk Factors. ANM. 2015;66(Suppl. 1):8–16.
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My granddaughter suffers from atopic dermatitis (AD) at a young age. The constant scratching causes little spots of bleeding and roughening of her baby skin. There doesn’t seem to be a cure for this condition. Even though I am an O&G specialist by trade, I have decided to read a little bit more on this topic and share them with you.
The prevalence of AD has doubled in Taiwan in the last 20 years. Some research shows industrialisation and air pollution may be risk factors whilst fish intake during pregnancy reduces infant risks of AD.
Eighty percent of AD starts below the age of 5. And about half of the children tend to “grow out of” AD. It may be mutli-factorial but the immune tolerance may be related to early control of AD.
Atopic dermatitis is a hypersensitivity reaction of the skin, many patients are found to have defects in their skin Filaggrin, which is a naturally-occurring skin moisturiser. Therefore skin emollient is an important treatment for the prevention of AD flares. Apart from the existing immunosuppression treatments (such as topical corticosteroids and calcineurin inhibitors), there are now biological agents available for the treatment of severe AD. The therapeutic armamentarium against AD is slowly increasing as we understand more about the disease.
Many variants of mutation at the Filaggrin gene have been found in up to 70% of patients with AD. There are currently 50-60 disease-causing variants known. Interestingly, mutations found in the European population seem to be different from those found in the Asian population. The mutations specific to the Taiwanese population are yet to be found.
The consensus amongst international experts seems to agree that early treatment of AD reduces recurrence and severities. However, it would be interesting to know the utility of early moisturizer application in those testing positive for Filaggrin gene but without AD.
skin disease research 在 謙預 Qianyu.sg Facebook 的最佳貼文
【川崎症 - 燒壞兒童心臟的殺手】
This disease had killed young children in Singapore.
Yesterday was the first time I had heard of the Kawasaki disease 川崎症 from a new client.
A Japanese doctor, Dr Tomisaku Kawasaki, first saw this in a 4-year old child in January 1961. He didn't know what was wrong and found no reference in the medical literature.
A year later, he saw the same disease in another child. That was his Eureka moment. It was an illness that did not exist in any medical textbook.
While a doctor brushed off Dr Kawasaki's hypothesis as "this may be just a scarlet fever", he persisted and eventually got this disease recognized in Japan in 1967, some 6 years later.
It is a disease that mainly affects children under 5 years old of all races and all continents. The blood vessels in the body gets inflamed and the child starts having a fever that can't be brought down with just aspirin. Usually it gets mistaken as "the usual viral fever".
Recently in Singapore, a pediatrician got suspended for misdiagnosing a 1-year old at Gleneagles Hospital. She failed to conduct the tests to confirm or rule out Kawasaki Disease, even though she thought of it. She continued treating it as a viral fever.
Other symptoms like strawberry tongue, swollen lymph nodes, red eyes, peeling skin, rashes in the groin, hands and feet and swollen red lips may start appearing in varying degrees.
It requires a echocardiogram to see if the child has heart problems and inflammation of coronary artieries, which supply blood to the heart muscles.
The first 10 days are critical for effective treatment. Miss this golden period and...
What is the worse that can happen?
Your young child can die from a heart attack. Happened in Singapore.
There are many young parents among my friends here. So I am writing this to spread awareness.
Over 6000 research papers have been written on the Kawasaki disease but no one could find the cause or etiology for this disease. So there is no vaccine or any way to prevent a child from contracting it. It is usually curable when detected early. Most children recover with no serious problems.
When my client shared with me what happened to her child, I immediately knew the Bazi and Feng Shui factors, that could lead up to a disease like this.
There are about 200 cases of Kawasaki Disease in Singapore a year.
50 years since its discovery, it still gets grossly misdiagnosed despite so many medical advancements.
The more we know about this disease, the more we can prevent other children and parents from suffering.
On a side note, remember to buy hospitalisation insurance for your children and do not hesitate to bring your child to the hospital or seek a second opinion, when the "normal" fever refuses to go away. Trust your parental instinct. Aspirin doesn't cure everything.
Photo credit: Intech
skin disease research 在 [email protected] Youtube 的最佳貼文
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(一)異位性皮膚炎是什麼? 00:07
(二)異位性皮膚炎成因? 00:39
(三)患上異位性皮膚炎需要戒口嗎? 01:13
(四)「濕疹鐵三角」可以治療異位性皮膚炎嗎? 2:20
(本短片作健康教育之用,並不可取代任何醫療診斷或治療。治療成效因人而異,如有疑問,請向專業醫療人士諮詢。)
參考資料:
1. Al-Shobaili, H. A., Ahmed, A. A., Alnomair, N., Alobead, Z. A., & Rasheed, Z. (2016). Molecular Genetic of Atopic dermatitis: An Update. International journal of health sciences, 10(1), 96–120.
2. Kanda, N., Hoashi, T., & Saeki, H. (2019). The Roles of Sex Hormones in the Course of Atopic Dermatitis. International journal of molecular sciences, 20(19), 4660. https://doi.org/10.3390/ijms20194660
3. Drislane, C., & Irvine, A. D. (2020). The role of filaggrin in atopic dermatitis and allergic disease. Annals of Allergy, Asthma & Immunology, 124(1), 36-43. doi:10.1016/j.anai.2019.10.008
4. Suárez, A. L., Feramisco, J. D., Koo, J., & Steinhoff, M. (2012). Psychoneuroimmunology of psychological stress and atopic dermatitis: pathophysiologic and therapeutic updates. Acta dermato-venereologica, 92(1), 7–15. https://doi.org/10.2340/00015555-1188
5. Dhar, S., & Srinivas, S. M. (2016). Food Allergy in Atopic Dermatitis. Indian journal of dermatology, 61(6), 645–648. https://doi.org/10.4103/0019-5154.193673
6. Yu, W. (2001). The Role of Food Allergy in Atopic Dermatitis in Children. Hong Kong Dermatology & Venereology Bulletin, 9(3), 110-116.
7. Lee, S. Y., Lee, E., Park, Y. M., & Hong, S. J. (2018). Microbiome in the Gut-Skin Axis in Atopic Dermatitis. Allergy, asthma & immunology research, 10(4), 354–362. https://doi.org/10.4168/aair.2018.10.4.354
8. Lee SY, Lee E, Park YM, Hong SJ. Microbiome in the Gut-Skin Axis in Atopic Dermatitis. Allergy Asthma Immunol Res. 2018 Jul;10(4):354-362. doi: 10.4168/aair.2018.10.4.354. PMID: 29949831; PMCID: PMC6021588.
9. Kim, H., Ban, J., Park, M. R., Kim, D. S., Kim, H. Y., Han, Y., Ahn, K., & Kim, J. (2012). Effect of bathing on atopic dermatitis during the summer season. Asia Pacific allergy, 2(4), 269–274. https://doi.org/10.5415/apallergy.2012.2.4.269
10. Ozkoca, Kutlubay, & Karakus. (2019). Treatment of Atopic Dermatitis: What’s New? Clinical Dermatology: Research and Therapy.
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查詢醫生資訊:
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skin disease research 在 Gobby Hong Youtube 的最佳解答
條片成10分鐘ga... 大家好拎定薯片同野飲坐定定睇啦~ ^3^
高比自家10個「初榨冷壓」椰子油妙用:
1) 頭髮用|亮髮焗油 Pre-wash Hair Treatment
有片睇:http://youtu.be/U4yd8KKOVh8
2) 頭皮用|防屑護理 Scalp Treatment
3) 清潔用|深層卸妝油 Makeup Remover
有片睇:http://youtu.be/C2LAKfjfUQs
4) 美顏用|抗皺護膚油 Anti-wrinkle oil
5) 濕疹用|身體潤膚油 Body Moisturiser
6) 滑溜用|脫毛前打底油 Shave Cream
7) 身體用|DIY黑糖磨沙 Body Scrub
8) 美甲用|指甲邊緣油 Cuticle oil
9) 保健用|能量及代謝催化劑 Energy & Metabolism booster
10) 煮食用|高"煙點"煮食油 High-heat cooking oil
如有疑問,歡迎留言發問討論。:)
部份Wiki資料,可供參考,英文比較詳盡喔~!!!
http://en.wikipedia.org/wiki/Coconut_oil
http://zh.wikipedia.org/wiki/%E6%A4%B0%E5%AD%90%E6%B2%B9
另有同學關注椰子油係膽固醇同塞血管性既疑慮,有關新聞可參考以下兩則文章:
蘋果新聞:http://hk.apple.nextmedia.com/supplement/columnist/3763978/art/20120626/16458829
英文文章(去heart disease個一項去睇啦):
http://www.cspinet.org/nah/articles/coconut-oil.html
______________________________
我食開的兩款初榨冷壓椰子油,iherb.com買到喔~
高比快要變代言人啦~ :P
• Nutiva, Organic Extra Virgin Coconut Oil, 15 fl oz (444 ml)
https://iherb.co/3wSJTsN7
• Nature's Way, Organic Coconut Oil, 16 oz (454 g)
https://iherb.co/q1RTUN6G
______________________________
網址:https://iherb.co/cgoCEP4Y
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Subscribe if you like !!! ^^
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skin disease research 在 Burden of skin disease - American Academy of Dermatology 的相關結果
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